Giornale Italiano di Endodonzia https://www.giornaleitalianoendodonzia.it/gie <p>The<strong> Giornale Italiano di Endodonzia</strong> was founded in 1987 and is the official journal of the <em>Italian Society of Endodontics (SIE)</em>. It is a peer-reviewed journal publishing original articles on clinical research and/or clinical methodology, case reports related to Endodontics. The Journal evaluates also contributes in restorative dentistry, dental traumatology, experimental pathophysiology, pharmacology and microbiology dealing with Endodontics. The <strong>Giornale Italiano di Endodonzia</strong> is indexed in <em>Scopus, </em> <em>Science Direct, Embase;</em> published online by <a title="AriesWebSite" href="http://www.ariesdue.it/" target="_blank" rel="noopener">Ariesdue</a>, Milan, Italy and hosted by <a href="http://www.pagepress.org/" target="_blank" rel="noopener">PAGEPress</a>, Pavia, Italy.</p> <p>The <strong>Giornale Italiano di Endodonzia</strong> publishes original scientific articles, reviews, clinical articles and case reports in the field of Endodontology. Scientific contributions dealing with health, injuries to and diseases of the pulp and periradicular region, and their relationship with systemic well-being and health. Original scientific articles are published in the areas of biomedical science, applied materials science, bioengineering, epidemiology and social science relevant to endodontic disease and its management, and to the restoration of root-treated teeth. In addition, review articles, reports of clinical cases, book reviews, summaries and abstracts of scientific meetings and news items are accepted. </p> ©Ariesdue srl, Milan, Italy. Online version powered by PAGEPress Publications, Pavia, Italy en-US Giornale Italiano di Endodonzia 1121-4171 <p><strong>Giornale Italiano di Endodonzia</strong> has chosen to apply the <a href="http://creativecommons.org/licenses/by-nc/4.0/" target="_blank" rel="noopener"><strong>Creative Commons Attribution NonCommercial 4.0 International License</strong></a> (CC BY-NC 4.0) to all manuscripts to be published.</p> The modern management of endodontic complications https://www.giornaleitalianoendodonzia.it/gie/article/view/463 <p>not available</p> Sandro Rengo Copyright (c) 2024 Sandro Rengo https://creativecommons.org/licenses/by-nc/4.0 2024-03-21 2024-03-21 38 1 10.32067/GIE.2024.38.01.05 Assessing dentinal tubule penetration of an innovative bioactive glass-based root canal sealer through confocal laser scanning microscopy: an in vitro analysis https://www.giornaleitalianoendodonzia.it/gie/article/view/457 <div> <p class="Default"><strong><span lang="EN-US">Aim:</span></strong><span lang="EN-US"> To assess and compare the dentinal tubule penetration of zinc oxide eugenol (ZOE)-based, resin-based, bioceramic, and novel bioactive glass-based root canal sealers using a confocal laser scanning microscope (CLSM). </span></p> </div> <div> <p class="Default"><strong><span lang="EN-US">Methods</span></strong><span lang="EN-US">: A total of 48 single-rooted permanent teeth were categorized into four groups (n=12) and treated with gutta-percha along with ZOE sealer (Tubli-Seal EWT), resin-based sealer (AH Plus), bioceramic sealer (BioRoot RCS), and bioactive glass (Nishika Canal Sealer-BG). Cross-sections of the roots at 3 mm and 6 mm from the apex were examined under a CLSM to evaluate dentinal tubule penetration. </span></p> </div> <div> <p class="Default"><strong><span lang="EN-US">Results:</span></strong><span lang="EN-US"> Results indicated that bioceramic sealers exhibited the highest depth of dentinal tubule penetration at both levels, followed by bioactive glass and resin-based sealers. ZOE-based sealer demonstrated the least tubule penetration. Bioactive glass displayed the highest percentage of sealer penetration at 3 mm and 6 mm, with no statistically significant difference observed between bioceramic and bioactive glass groups regarding depth and percentage of dentinal tubule penetration at both levels. </span></p> </div> <div> <p class="Default"><strong><span lang="EN-US">Conclusions:</span></strong> <span lang="EN-US">Of particular significance is the bioactive glass group, demonstrating the most substantial sealer penetration percentage compared to the other groups at both examined depths.</span></p> </div> Sourabh Barbhai Srinidhi SR Rajesh Shetty Poonam Joshi Vini Mehta Aida Meto Copyright (c) 2024 Sourabh Barbhai, Srinidhi SR, Rajesh Shetty, Poonam Joshi, Vini Mehta, Aida Meto https://creativecommons.org/licenses/by-nc/4.0 2024-03-26 2024-03-26 38 1 10.32067/GIE.2024.38.01.06 Applicability of photobiomodulation and antimicrobial photodynamic therapy for pain management after endodontic treatment: a randomized clinical trial https://www.giornaleitalianoendodonzia.it/gie/article/view/456 <p><strong>Aim</strong>: To evaluate the use of photobiomodulation (PBM), alone or combined with antimicrobial photodynamic therapy (aPDT), for pain management after endodontic treatment.</p> <p><strong>Methodology</strong>: Randomized parallel-group superiority trial. The allocation sequence was generated using an online true random number generator. To ensure blinding, participants were informed about the study and the devices that would be used, but not about group allocation. Ninety mandibular molars diagnosed with symptomatic irreversible pulpitis were selected and randomly divided into three groups (n=30): Group 1, control (CT); Group 2, photobiomodulation (PBM); and Group 3, PBM + aPDT. All canals were instrumented by the Reciproc system in a single visit. The incidence and intensity of pain were evaluated before and 6, 12, 24, and 48 hours after endodontic treatment, using a visual analogue scale (VAS). The results were analysed using the Kruskal–Wallis test followed by Dunn’s test.</p> <p><strong>Results</strong>: The combination of PBM and aPDT after conventional endodontic treatment resulted in a significant reduction in pain compared to conventional endodontic treatment alone or followed by PBM alone (p&lt;0.05). Preoperative pain was significantly greater than pain at 6, 12, 24, and 48 hours after endodontic treatment (p&lt;0.05) in all groups. There were no adverse effects attributable to low-level light therapy in any participants.</p> <p><strong>Conclusion</strong>: Our findings suggest that the combination of photobiomodulation and photodynamic therapy is a promising alternative for this purpose.</p> Monique de Carvalho Souza Alexandre Sigrist De Martin Daniel Guimarães Pedro Rocha Carlos Eduardo Fontana Rina Andréia Pelegrine Carlos Eduardo da Silveira Bueno Diana Roberta Pereira Grandizoli Sérgio Luiz Pinheiro Copyright (c) 2024 Monique de Carvalho Souza, Alexandre Sigrist De Martin, Daniel Guimarães Pedro Rocha, Carlos Eduardo Fontana, Rina Andréia Pelegrine, Carlos Eduardo da Silveira Bueno, Diana Roberta Pereira Grandizoli, Sérgio Luiz Pinheiro https://creativecommons.org/licenses/by-nc/4.0 2024-04-09 2024-04-09 38 1 10.32067/GIE.2024.38.01.07 Treatment planning and therapy of a severely compromised two-rooted maxillary central incisor https://www.giornaleitalianoendodonzia.it/gie/article/view/447 <p><strong>Aim:</strong> This case report presents the diagnosis and therapy of a severally compromised two-canal maxillary central incisor.</p> <p><strong>Summary:</strong> Tooth #21 was refereed for treatment. 2D and 3D Radiographic evaluation revealed the presence of a severely compromised two-canal central incisor. Root canal therapy was performed. In the two-year follow-up the tooth was fully functional.</p> <p><strong>Key learning points:</strong></p> <p><em>• </em>Meticulous treatment planning and treatment is a valid option even in complicated and compromised cases. </p> <p class="p1">• Root canal treatment can provide concrete therapeutical choices even in heavily compromised cases.</p> Andreas Krokidis Antonio Cerutti Copyright (c) 2024 Andreas Krokidis, Antonio Cerutti https://creativecommons.org/licenses/by-nc/4.0 2024-02-06 2024-02-06 38 1 10.32067/GIE.2024.38.01.01 Root canal treatment of a maxillary first molar with unusual anatomy: a case report https://www.giornaleitalianoendodonzia.it/gie/article/view/446 <p><strong>Aim:</strong> To describe the management of a maxillary first molar with six root canals, two in each root.</p> <p><strong>Summary:</strong> A 36-year-old male patient presented with a complaint of discoloration and decay on an upper left back tooth. Clinical examination revealed the presence of deep occlusal caries on the maxillary left first molar. A detailed clinical and radiographical examination led to a diagnosis of pulp necrosis with asymptomatic apical periodontitis. Non-surgical root canal treatment was performed. Due to the suspected anatomical variation, Cone beam computed tomography (CBCT) imaging was obtained. CBCT imaging and clinical identification using the DOM revealed the presence of six root canals, two in each root, with the code (<sup>3</sup>26 MB<sup>2 </sup>DB<sup>2 </sup>P<sup>2-1</sup>) using Ahmed et al. system. Root canal treatment was successfully performed and confirmed radiographically. The tooth was restored with a resin composite restoration. The patient was referred for prosthodontic evaluation for extracoronal restoration.</p> <p><strong>Key learning points:</strong></p> <ul> <li>This case highlights how clinicians must approach root canal treatment with a comprehensive mindset that considers the potential for extraordinary anatomical complexities.</li> <li>Preoperative knowledge of root canal anatomy and proper armamentarium are mandatory for successful root canal treatment procedures.</li> </ul> Archika Singh Tarek Elsewify Ranya Elemam Bassem Eid Hany M.A. Ahmed Copyright (c) 2024 Archika Singh, Tarek Elsewify, Ranya Elemam, Bassem Eid, Hany M.A. Ahmed https://creativecommons.org/licenses/by-nc/4.0 2024-03-14 2024-03-14 38 1 10.32067/GIE.2023.37.01.32